Breast Cancer Gene Awareness During Breast Cancer Awareness Month

 

Breast Cancer Gene Awareness During Breast Cancer Awareness Month

Introduction:

One of the most common concerns I come across is the hesitancy among women to undergo genetic testing due to fear of potential revelations. Recent data from U.S. News and World Report suggests that approximately 87% of newly diagnosed breast cancer patients have undergone BRCA testing, which empowers them to make informed decisions regarding their treatment. With breast cancer affecting 1 in 8 women in the general population, understanding the significance of BRCA1 and BRCA2 genetic mutations becomes increasingly important.

Understanding BRCA1 and BRCA2:

BRCA1 and BRCA2 genes, often pronounced as "braca," are integral to everyone's genetic makeup. However, some individuals carry mutations in these genes, substantially elevating their risk of breast and ovarian cancer. These abbreviations stem from the researchers who discovered them, with BRCA standing for BReast CAncer 1 and BReast CAncer susceptibility gene 2. Importantly, these mutations are hereditary, meaning they can be passed down from one generation to the next. In the United States, excluding individuals with Ashkenazi Jewish ancestry, approximately 1 in 400 people carries a BRCA1 or BRCA2 gene mutation. For those of Ashkenazi Jewish descent, this figure increases to about 1 in 40.

Who Should Consider Genetic Testing:

The National Comprehensive Cancer Network (NCCN) advises genetic testing for those with a high risk of inheriting a gene mutation or when it can inform breast cancer treatment decisions. Additionally, individuals with a 2.5% to 5% or higher chance of possessing a BRCA1 or BRCA2 gene mutation, as estimated through a family history-based risk assessment model, should consider testing. Doctors evaluate potential indicators such as:

1. Two first-degree family members (mother, daughter, sister) with breast cancer, especially if one was diagnosed at age 50 or younger.

2. Three or more first or second-degree relatives with breast cancer.

3. A first-degree relative with cancer diagnosed in both breasts.

4. Breast cancer occurrence in a male relative.

Cost Considerations:

While BRCA gene mutation testing can be expensive, it's crucial to note that the Affordable Care Act mandates insurance coverage for eligible individuals based on family history and risk factors.

Navigating a Positive Result:

A positive BRCA gene mutation test result can be emotionally challenging, but it empowers individuals to proactively manage their health. You can collaborate with your healthcare provider to develop a tailored early detection plan, which is key to more effective cancer treatment. This may involve earlier and more frequent breast cancer screenings, alongside additional imaging techniques like MRI or ultrasound. Women with high-risk BRCA mutations might also opt for preventative measures, including a double mastectomy to preempt cancer development.

Seeking Assistance:

If you suspect you qualify for low-cost or no-cost mammograms or BRCA genetic testing, please consult one of our partner institutions or contact us at 706-291-9998 for a referral. Healthcare providers and screening partners with patients in need of screenings are encouraged to reach out to us at 706-291-9998.

Conclusion:

This Thanksgiving, consider gathering your family for a discussion that could potentially save lives – a conversation about your family's medical history. By understanding your family's health background, you can better assess potential risks and promptly inform your healthcare provider of any updates. If you have concerns about your risk of breast cancer, remember that your healthcare provider is your ally in making informed decisions about genetic testing and preventative measures. Knowledge truly is power when it comes to managing your health.